A Japanese Case of Esophageal Lichen Planus that Was Successfully Treated with Systemic Corticosteroids

نویسندگان

  • Yuki Sato
  • Ryuta Takenaka
  • Akihiro Matsumi
  • Kensuke Takei
  • Shotaro Okanoue
  • Eriko Yasutomi
  • Daisuke Kawai
  • Koji Takemoto
  • Hirofumi Tsugeno
  • Takayoshi Miyake
  • Shigeatsu Fujiki
چکیده

Esophageal lichen planus (ELP) is rare and only about 80 cases have been reported in the literature. An 85-year-old woman presented with dysphagia and odynophagia. Endoscopy revealed a severe stricture in the proximal esophagus. Oral examinations at two years after the first endoscopy revealed erosions around the gingiva, and an examination of biopsy specimens taken from the site of erosion led to a diagnosis of oral lichen planus. Esophageal endoscopy was performed again, and biopsy specimens showed spongiosis and necrotic keratinocytes in the epithelium (civatte bodies). The patient was diagnosed with ELP and was treated with systemic corticosteroids, which resulted in clinical relief.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Low dose Methotrexate for the treatment of generalized lichen planus

Background: Lichen planus is a common inflammatory disease that can involve the skin, nails, mucous membrane, and hair follicles. There is a long list of topical and systemic therapies for its treatment. Methotrexarte has some characteristics that make it a good choice for generalized lichen planus. Aim: The goal of this study was to assess the effect of low dose methotrexate in generalized lic...

متن کامل

Comparison of the narrow band UVB versus systemic corticosteroids in the treatment of lichen planus: A randomized clinical trial

BACKGROUND Lichen planus is recognized as an inflammatory disease of the skin with different morphologic patterns. Different treatment modalities, including topical and systemic corticosteroids, methotrexate, cyclosporine, azathioprine, topical calcineurin inhibitors, and psoralen plus UVA (PUVA), have been suggested for lichen planus. Although the efficacy of narrowband UVB (NBUVB) for treatme...

متن کامل

Acitretin for the management of generalized cutaneous lichen planus.

BACKGROUND Lichen planus is an inflammatory disease that affects the skin, the oral mucosa, or both. Generalized cutaneous lichen planus may pose a therapeutic challenge for clinicians if the condition persists or flares after topical or systemic corticosteroid therapy. PURPOSE Acitretin, a systemic retinoid, can be considered a potential second-line treatment for patients with generalized cu...

متن کامل

Case report and review of esophageal lichen planus treated with fluticasone.

Lichen planus is a fairly common chronic idiopathic disorder of the skin, nails and mucosal surfaces. Esophageal involvement of this disease on the other hand is rare and only about 50 cases have been reported in literature. Given its rarity, it can be difficult to diagnose and may be easily misdiagnosed as reflux esophagitis. Currently, there are no clear recommendations on the optimal managem...

متن کامل

A Case Report of Progressive Dysphagia and Pigmented Oral and Skin Lesions: Esophageal Lichen Planus

Lichen planus (LP) is a relatively uncommon, chronic inflammatory disease with idiopathic pathogenesis that usually involves skin, nails, and mucous membranes. Esophageal involvement in LP is rarely seen, despite the classification of the esophagus as a mucous membrane. Esophageal lichen planus is common in middle aged women, with symptoms such as dysphagia and odynophagia. This paper presents ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 57  شماره 

صفحات  -

تاریخ انتشار 2018